“Iron Deficiency Is Associated with Adverse Outcomes in Pediatric Heart Failure” was published in The Journal of Pediatrics on January 1, 2020. As the title suggests, this single-center retrospective cohort study revealed that iron deficiency in pediatric heart failure patients was associated with greater risk of ventricular assist device implantation, heart transplantation, or mortality.
The cohort consisted of 107 patients with heart failure aged 1-21 years from July 2012 to June 2017 with available serum iron studies. 56% of these patients were iron deficient. Approximately 50% of patients that had iron deficiency were not anemic. Notably, demographics, etiology of heart failure, and chronicity of heart failure symptoms were not associated with iron deficiency.
A team at Baylor College of Medicine / Texas Children’s Hospital made this work possible. ACTION members apart of this work include:
- Joseph Spinner
- Hari Tunuguntla
- Kriti Puri
- Jack Price
- Jacquelyn Powers
- Susan Denfield
- Antonio Cabrera
- William Dreyer
- Mona Shah
CITATION
Puri K, Price JF, Spinner JA, Powers JM, Denfield SW, Cabrera AG, Tunuguntla HP, Dreyer WJ, Shah MD. Iron Deficiency Is Associated with Adverse Outcomes in Pediatric Heart Failure. J Pediatr. 2020 Jan;216:58-66.e1. doi: 10.1016/j.jpeds.2019.08.060. Epub 2019 Oct 11. PMID: 31610927.
